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Product Introduction:
Aldehyde-activated SepFast 4 High Flow (4HF) is made of highly cross-linked 4% beaded agarose. Its large pore size is suitable for coupling or purifying large molecules. It also shows high mechanical rigidity allowing high flow throughput with reduced back pressure.
Agarose has long been used for chromatographic separations due to its excellent hydrophilic and low non-specific-binding nature. The particles have an open pore structure with excellent mass transfer properties to various molecules. The base matrix is activated through oxidation to generate aldehyde groups. It reacts directly with the primary amine groups in molecules to be immobilized in the presence of reducing agents. Aldehyde-activated SepFast media is supplied as an aqueous suspension in 20% ethanol.
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